86-7732-63　［取扱停止］c-Myc Polyclonal Antibody 100ul　ES2011

特徴

• Background：v-myc avian myelocytomatosis viral oncogene homolog(MYC) Homo sapiens The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IHC-p,IF,ELISA
• Species reactivity：Human,Mouse,Rat
• Immunogen：The antiserum was produced against synthesized peptide derived from human MYC. AA range:31-80
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：50,(also ~60KD in some samples)
• GeneID（Human）：MYC
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