86-7732-13　［取扱停止］TERT Polyclonal Antibody 100ul　ES7373

特徴

• Background：telomerase reverse transcriptase(TERT) Homo sapiens Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative sp

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,ELISA
• Species reactivity：Human
• Immunogen：The antiserum was produced against synthesized peptide derived from human Telomerase. AA range:796-845
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：130
• GeneID（Human）：TERT
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