86-7731-91　［取扱停止］SREBP-1 Polyclonal Antibody 100ul　ES4238

特徴

• Background：sterol regulatory element binding transcription factor 1(SREBF1) Homo sapiens This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,ELISA
• Species reactivity：Human,Mouse,Rat
• Immunogen：Synthesized peptide derived from the Internal region of human SREBP-1.
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：120
• GeneID（Human）：SREBF1
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