特徴
- Background:signal transducer and activator of transcription 6(STAT6) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
仕様
- サイズ:100ul
- Source:Rabbit
- Applications:WB,IHC-p,IP,ELISA
- Species reactivity:Human,Mouse,Rat
- Immunogen:The antiserum was produced against synthesized peptide derived from human STAT6. AA range:612-661
- Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:1 mg/ml
- Observed band:94
- GeneID(Human):STAT6
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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86-7731-06
Stat6 Polyclonal Antibody 100ul
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86-7731-04
Stat6 Polyclonal Antibody 100ul
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