特徴
- Background:transcription factor 3(TCF3) Homo sapiens This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have bee
仕様
- サイズ:100ul
- Source:Rabbit
- Applications:WB,IHC-p,ELISA
- Species reactivity:Human,Mouse,Rat
- Immunogen:The antiserum was produced against synthesized peptide derived from human TCF3. AA range:571-620
- Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:1 mg/ml
- Observed band:68
- GeneID(Human):TCF3
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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86-7729-57
TCF-3 Polyclonal Antibody 100ul
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86-7729-72
TCF-3 Polyclonal Antibody 100ul
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