86-7724-74　［取扱停止］NF kappa B-p105 Polyclonal Antibody 100ul　ES2945

特徴

• Background：nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IHC-p,IP,ELISA
• Species reactivity：Human
• Immunogen：The antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50. AA range:874-923
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：105
• GeneID（Human）：NFKB1
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