Background：elaC ribonuclease Z 2(ELAC2) Homo sapiens The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
仕様
サイズ：100ul
Source：Rabbit
Applications：IHC-p,ELISA
Species reactivity：Human
Immunogen：The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
