特徴
- Background：ATP binding cassette subfamily G member 2 (Junior blood group)(ABCG2) Homo sapiens The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：IF,WB,IHC-p,ELISA
- Species reactivity：Human
- Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：75
- GeneID（Human）：ABCG2
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7719-19
ABCG2 Polyclonal Antibody 100ul
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86-7717-75
ABCG2 Polyclonal Antibody 100ul
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