86-7717-71　MDM2 Polyclonal Antibody 100ul　ES3916

特徴

• Background：MDM2 proto-oncogene(MDM2) Homo sapiens This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：IF,WB,IHC-p,ELISA
• Species reactivity：Human
• Immunogen：The antiserum was produced against synthesized peptide derived from the C-terminal region of human MDM2. AA range:381-430
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：55
• GeneID（Human）：MDM2
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