86-7717-41　［取扱停止］p53 Polyclonal Antibody 100ul　ES3123

特徴

• Background：tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,ELISA
• Species reactivity：Human,Mouse,Rat
• Immunogen：The antiserum was produced against synthesized peptide derived from human p53. AA range:15-64
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：53
• GeneID（Human）：TP53
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