特徴
- Background：BCL2 associated athanogene 3(BAG3) Homo sapiens BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,IHC-p,ELISA
- Species reactivity：Human
- Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human BAG3. AA range:311-360
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：65
- GeneID（Human）：BAG3
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7716-30
Bag-3 Polyclonal Antibody 100ul
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86-7716-24
Bag-3 Polyclonal Antibody 100ul
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