特徴
- Background：Fas associated via death domain(FADD) Homo sapiens The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：IHC-p,IF,ELISA
- Species reactivity：Human
- Immunogen：The antiserum was produced against synthesized peptide derived from human FADD. AA range:101-150
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：23
- GeneID（Human）：FADD
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- アズワン株式会社 試薬・プロセス材料グループ
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7716-03
FADD Polyclonal Antibody 100ul
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86-7715-91
FADD Polyclonal Antibody 100ul
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86-7716-02
FADD Polyclonal Antibody 100ul
|
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掲載カタログ情報
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