Background：RAD18, E3 ubiquitin protein ligase(RAD18) Homo sapiens The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008],
仕様
サイズ：100ul
Source：Rabbit
Applications：WB,ELISA
Species reactivity：Human,Rat
Immunogen：The antiserum was produced against synthesized peptide derived from human RAD18. AA range:301-350
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
