特徴
- Background：DNA fragmentation factor subunit alpha(DFFA) Homo sapiens Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,IHC-p,ELISA
- Species reactivity：Human
- Immunogen：The antiserum was produced against synthesized peptide derived from human DFFA. AA range:175-224
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：37
- GeneID（Human）：DFFA
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7715-54
ICAD Polyclonal Antibody 100ul
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86-7715-45
ICAD Polyclonal Antibody 100ul
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