特徴
- Background：MRE11 homolog, double strand break repair nuclease(MRE11) Homo sapiens This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,IHC-p,ELISA
- Species reactivity：Human,Mouse,Rat,Monkey
- Immunogen：The antiserum was produced against synthesized peptide derived from human MRE11. AA range:230-279
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：80
- GeneID（Human）：MRE11A
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7714-02
MRE11 Polyclonal Antibody 100ul
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86-7714-89
MRE11 Polyclonal Antibody 100ul
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