Background:DNA ligase 1(LIG1) Homo sapiens This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,IHC-p,ELISA
Species reactivity:Human
Immunogen:The antiserum was produced against synthesized peptide derived from human DNL1. AA range:111-160
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.