Background:granzyme H(GZMH) Homo sapiens This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015],
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,IHC-p,IF,ELISA
Species reactivity:Human
Immunogen:The antiserum was produced against synthesized peptide derived from human GRAH. AA range:51-100
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.