Background：Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
仕様
サイズ：100ug
Host：Mouse
Specificity：Human, Mouse, Rat
Clonality：monoclonal
Application：ELISA, IHC, WB
Isotype：IgG1
Form：liquid
Purification：protein A+G purified
Purity：≥95% as determined by SDS-PAGE
Immunogen：synuclein, alpha (non A4 component of amyloid precursor)
