Background：Zinc-alpha-2-glycoprotein(AZGP1) is a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor(PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex(MHC) antigens(PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors(PMID: 22625427).
