Background:The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse, Rat
Clonality:polyclonal
Application:ELISA, WB, IHC, IF
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:X-ray repair complementing defective repair in Chinese hamster cells 4