Background:Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers(CPD), sites of DNA damage after UV irradiation.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse, Rat
Clonality:polyclonal
Application:ELISA, WB
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:xeroderma pigmentosum, complementation group A