Background：Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:25447204). With OSBPL3, may regulate ER morphology(PubMed:16143324). May play a role in vesicle trafficking(PubMed:11511104, PubMed:19289470).
仕様
サイズ：100ug
Host：Rabbit
Specificity：Human, Mouse, Rat
Clonality：polyclonal
Application：ELISA, WB, IHC, IF, IP
Isotype：IgG
Form：liquid
Purification：Immunogen affinity purified
Purity：≥95% as determined by SDS-PAGE
Immunogen：VAMP(vesicle-associated membrane protein)-associated protein A, 33kDa
