Background：Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
仕様
サイズ：100ug
Host：Mouse
Specificity：Human
Clonality：monoclonal
Application：ELISA, WB
Isotype：IgG1
Form：liquid
Purification：Protein A+G purification
Purity：≥95% as determined by SDS-PAGE
Immunogen：transducin-like enhancer of split 1(E(sp1) homolog, Drosophila)
