Background:Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily(RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse, Rat
Clonality:polyclonal
Application:ELISA, WB, IHC
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:RAB3 GTPase activating protein subunit 2(non-catalytic)