Background：May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.
仕様
サイズ：100ug
Host：Rabbit
Specificity：Human, Mouse
Clonality：polyclonal
Application：ELISA, WB, IF, IHC
Isotype：IgG
Form：liquid
Purification：Immunogen affinity purified
Purity：≥95% as determined by SDS-PAGE
Immunogen：pleckstrin homology domain containing, family F(with FYVE domain) member 1
