Background：Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).
仕様
サイズ：100ug
Host：Mouse
Specificity：Human
Clonality：monoclonal
Application：ELISA, WB, IHC
Isotype：IgG1
Form：liquid
Purification：Protein A+G purification
Purity：≥95% as determined by SDS-PAGE
Immunogen：programmed cell death 4(neoplastic transformation inhibitor)
