Background：Dock4 is a member of the dedicator of cytokinesis(DOCK) family and encodes a protein with a DHR-1(CZH-1) domain, a DHR-2(CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers.
仕様
サイズ：100ug
Host：Rabbit
Specificity：Human, Mouse, Rat
Clonality：polyclonal
Application：ELISA, IHC
Isotype：IgG
Form：liquid
Purification：Immunogen affinity purified
Purity：≥95% as determined by SDS-PAGE
Immunogen：bone gamma-carboxyglutamate(gla) protein
