Background：Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
仕様
サイズ：100ug
Host：Mouse
Specificity：Human, Mouse, Rat
Clonality：monoclonal
Application：ELISA, IHC, WB
Isotype：IgG2a
Form：liquid
Purification：Protein A+G purification
Purity：≥95% as determined by SDS-PAGE
Immunogen：cadherin 2, type 1, N-cadherin(neuronal)
