Background:S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1145(Gm1145) in the 16S mitochondrial large subunit ribosomal RNA(mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.