Background：Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex(RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC.
(Microbial infection) Required for RNA-directed transcription and replication of the human hepatitis delta virus(HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
