Background:E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse
Clonality:polyclonal
Application:ELISA, WB, IP
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:membrane-associated ring finger(C3HC4) 8