Background:Functional component of the Nogo receptor signaling complex(RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors(PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination(PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development(By similarity).
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse, Rat
Clonality:polyclonal
Application:ELISA, WB
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:leucine rich repeat and Ig domain containing 1