86-5892-94　anti- KLHL22 antibody 100ug　FNab04620

特徴

• Background：Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.

仕様

• サイズ：100ug
• Host：Rabbit
• Specificity：Human, Mouse, Rat
• Clonality：polyclonal
• Application：ELISA, WB
• Isotype：IgG
• Form：liquid
• Purification：Immunogen affinity purified
• Purity：≥95% as determined by SDS-PAGE
• Immunogen：kelch-like 22(Drosophila)
• Manual Links：https://static.fn-test.com/product/manuals/antibody/FNab04620.pdf

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]