86-5889-15　anti- IL17RC antibody 100ug　FNab04231

特徴

• Background：Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495).
• Isoform 5: Receptor for both IL17A and IL17F.
• Isoform 6: Does not bind IL17A or IL17F.
• Isoform 7: Does not bind IL17A or IL17F.
• Isoform 8: Receptor for both IL17A and IL17F.

仕様

• サイズ：100ug
• Host：Rabbit
• Specificity：Human, Mouse
• Clonality：polyclonal
• Application：ELISA, WB
• Isotype：IgG
• Form：liquid
• Purification：Immunogen affinity purified
• Purity：≥95% as determined by SDS-PAGE
• Immunogen：interleukin 17 receptor C
• Manual Links：https://static.fn-test.com/product/manuals/antibody/FNab04231.pdf

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