Background：This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
仕様
サイズ：100ug
Host：Rabbit
Specificity：Human, Mouse, Rat, Pig
Clonality：polyclonal
Application：ELISA, IHC, IF, WB, IP, FC
Isotype：IgG
Form：liquid
Purification：Immunogen affinity purified
Purity：≥95% as determined by SDS-PAGE
Immunogen：nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
