Background：Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS(PubMed:24245781).
仕様
サイズ：100ug
Host：Mouse
Specificity：Human, Mouse
Clonality：monoclonal
Application：ELISA, WB
Isotype：IgG1
Form：liquid
Purification：Protein A+G purification
Purity：≥95% as determined by SDS-PAGE
Immunogen：GATA binding protein 1(globin transcription factor 1)
