Background:Hydroxylates arachidonic acid(20:4n-6) to(18R)-hydroxyarachidonate. Shows little activity against prostaglandin(PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid(22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid(22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid(22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human
Clonality:polyclonal
Application:ELISA, IHC
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:cytochrome P450, family 4, subfamily F, polypeptide 8