Background：BIRC2(also known as cIAP1) is a member of the inhibitor of apoptosis protein(IAP) family. The inhibitor of apoptosis(IAP) proteins are a family of anti-apoptotic regulators found in viruses and metazoans. BIRC2 is a nuclear shuttling protein, whose subcellular localization is mediated by the CRM1-dependent nuclear export pathway(PMID: 15265700). This cIAP1 antibody can bind both full length(70kd) and cleaved form(60kd) of the protein.
