Background：Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
仕様
サイズ：100ug
Host：Rabbit
Specificity：Human
Clonality：polyclonal
Application：ELISA, WB, IHC, FC, IF
Isotype：IgG
Form：liquid
Purification：Immunogen affinity purified
Purity：≥95% as determined by SDS-PAGE
Immunogen：CD59 molecule, complement regulatory protein
