86-5850-57　anti- ALKBH5 antibody 100ug　FNab00314

特徴

• Background：Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).

仕様

• サイズ：100ug
• Host：Rabbit
• Specificity：Human, Mouse, Rat
• Clonality：polyclonal
• Application：ELISA, WB
• Isotype：IgG
• Form：liquid
• Purification：Immunogen affinity purified
• Purity：≥95% as determined by SDS-PAGE
• Immunogen：alkB, alkylation repair homolog 5(E. coli)
• Manual Links：https://static.fn-test.com/product/manuals/antibody/FNab00314.pdf

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