Background:The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse
Clonality:polyclonal
Application:ELISA, WB, IHC, IF
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)