Background：Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
仕様
サイズ：100ug
Host：Mouse
Specificity：Human, Mouse
Clonality：monoclonal
Application：ELISA, WB
Isotype：IgG2a
Form：liquid
Purification：Protein A+G purification
Purity：≥95% as determined by SDS-PAGE
Immunogen：adiponectin, C1Q and collagen domain containing
