Background:Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
仕様
サイズ:100ug
Host:Rabbit
Specificity:Human, Mouse, Rat
Clonality:polyclonal
Application:ELISA, IHC, WB
Isotype:IgG
Form:liquid
Purification:Immunogen affinity purified
Purity:≥95% as determined by SDS-PAGE
Immunogen:mitogen-activated protein kinase kinase kinase 7 interacting protein 2