86-4361-32 WNT5A Antibody 50ug CSB-PA026138LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]
特徴
- Background：Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.
仕様
- Aliases：Protein Wnt-5a, WNT5A
- Product Type：Polyclonal Antibody
- Immunogen Species：Human
- uniprot ID：P41221
- Immunogen：Recombinant Human Protein Wnt-5a protein （62-380AA）
- Host Species：Rabbit
- Species Reactivity：Human, Mouse
- Tested Applications：ELISA, WB, IHC, IF
- Clonality：Polyclonal
- Isotype：IgG
- Conjugate：Non-conjugated
- Buffer：Preservative： 0.03％ Proclin 300＜br /＞Constituents： 50％ Glycerol, 0.01M PBS, pH 7.4
- Form：Liquid
- Purification Method：＞95％, Protein G purified
- Target Names：WNT5A
- Research Area：Neuroscience
- サイズ：50ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4361-31
WNT5A Antibody 100ug
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86-4361-32
WNT5A Antibody 50ug
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