86-4360-79 ULBP1 Antibody 50ug CSB-PA887177LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]特徴
- Background:Ligand for the KLRK1/NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
仕様
- Aliases:UL16-binding protein 1 (ALCAN-beta) (NKG2D ligand 1) (N2DL-1) (NKG2DL1) (Retinoic acid early transcript 1I), ULBP1, N2DL1 RAET1I
- Product Type:Polyclonal Antibody
- Immunogen Species:Human
- uniprot ID:Q9BZM6
- Immunogen:Recombinant Human UL16-binding protein 1 protein (26-216AA)
- Host Species:Rabbit
- Species Reactivity:Human
- Tested Applications:ELISA, IHC, IF
- Clonality:Polyclonal
- Isotype:IgG
- Conjugate:Non-conjugated
- Buffer:Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Form:Liquid
- Purification Method:>95%, Protein G purified
- Target Names:ULBP1
- Research Area:Immunology
- サイズ:50ug
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86-4360-78
ULBP1 Antibody 100ug
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86-4360-79
ULBP1 Antibody 50ug
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