86-4358-38 SIRPA Antibody, Biotin conjugated 100ug CSB-PA021334LD01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]特徴
- Background:Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
仕様
- Aliases:Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a), SIRPA, BIT MFR MYD1 PTPNS1 SHPS1 SIRP
- Product Type:Polyclonal Antibody
- Immunogen Species:Human
- uniprot ID:P78324
- Immunogen:Recombinant Human Tyrosine-protein phosphatase non-receptor type substrate 1 protein (31-373AA)
- Host Species:Rabbit
- Species Reactivity:Human
- Tested Applications:ELISA
- Clonality:Polyclonal
- Isotype:IgG
- Conjugate:Biotin
- Buffer:Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Form:Liquid
- Purification Method:>95%, Protein G purified
- Target Names:SIRPA
- Research Area:Neuroscience
- サイズ:100ug
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
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86-4358-39
SIRPA Antibody, Biotin conjugated 50ug
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86-4358-38
SIRPA Antibody, Biotin conjugated 100ug
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