86-4354-22 N Antibody 50ug CSB-PA318492LA01JAM
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]
特徴
- Background：Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid （NC）. Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon （IFNB） production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation （By similarity）. Interacts with host IKBKE （via Protein kinase domain）; the interaction inhibits IKBKE kinase activity.
仕様
- Aliases：Nucleoprotein （Nucleocapsid protein） （Protein N）, N
- Product Type：Polyclonal Antibody
- Immunogen Species：Junin mammarenavirus
- uniprot ID：P14239
- Immunogen：Recombinant Junin mammarenavirus Nucleoprotein protein （1-564AA）
- Host Species：Rabbit
- Species Reactivity：Junin mammarenavirus
- Tested Applications：ELISA, WB
- Clonality：Polyclonal
- Isotype：IgG
- Conjugate：Non-conjugated
- Buffer：Preservative： 0.03％ Proclin 300＜br /＞Constituents： 50％ Glycerol, 0.01M PBS, pH 7.4
- Form：Liquid
- Purification Method：＞95％, Protein G purified
- Target Names：N
- Research Area：Others
- サイズ：50ug
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-4354-24
N Antibody 50ul
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86-4354-27
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86-4354-28
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86-4354-22
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86-4354-25
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86-4354-29
N Antibody 50ul
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86-4354-21
N Antibody 100ul
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86-4354-23
N Antibody 50ul
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86-4354-26
N Antibody 50ul
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