86-4353-52 MITF Antibody, FITC conjugated 50ul CSB-PA014595LC01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]特徴
- Background:Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
仕様
- Aliases:Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32), MITF, BHLHE32
- Product Type:Polyclonal
- Immunogen Species:Human
- uniprot ID:O75030
- Immunogen:Recombinant Human Microphthalmia-associated transcription factor protein (40-269aa)
- Host Species:Rabbit
- Species Reactivity:Human
- Tested Applications:ELISA
- Clonality:Polyclonal
- Isotype:IgG
- Conjugate:FITC
- Buffer:Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Form:Liquid
- Purification Method:>95%, Protein G purified
- Target Names:MITF
- Research Area:Epigenetics and Nuclear Signaling
- サイズ:50ul
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86-4353-52
MITF Antibody, FITC conjugated 50ul
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86-4353-51
MITF Antibody, FITC conjugated 100ul
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