86-4353-45 [取扱停止]METTL14 Antibody 100ug CSB-PA884519LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]特徴
- Background:N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (By similarity).
仕様
- Aliases:N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14), METTL14, KIAA1627
- Product Type:Polyclonal Antibody
- Immunogen Species:Human
- uniprot ID:Q9HCE5
- Immunogen:Recombinant Human N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA)
- Host Species:Rabbit
- Species Reactivity:Human
- Tested Applications:ELISA, WB, IHC
- Clonality:Polyclonal
- Isotype:IgG
- Conjugate:Non-conjugated
- Buffer:Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Form:Liquid
- Purification Method:>95%, Protein G purified
- Target Names:METTL14
- Research Area:Cell Biology
- サイズ:100ug
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| 商品イメージ | アズワン品番 商品名 |
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86-4353-46
METTL14 Antibody 50ug
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86-4353-45
METTL14 Antibody 100ug
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