86-4352-16 ［取扱停止］KLRK1 Antibody 100ug CSB-PA012474LA01HU
[WUHAN HUAMEI BIOTECH Co.,Ltd(CUSABIO)]
特徴
- Background：Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer （NK） cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor （TCR） in CD8（+） T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 （ULBP2＞ULBP1＞ULBP3） and ULBP4.
仕様
- Aliases：NKG2-D type II integral membrane protein （Killer cell lectin-like receptor subfamily K member 1） （NK cell receptor D） （NKG2-D-activating NK receptor） （CD antigen CD314）, KLRK1, D12S2489E NKG2D
- Product Type：Polyclonal Antibody
- Immunogen Species：Human
- uniprot ID：P26718
- Immunogen：Recombinant Human NKG2-D type II integral membrane protein （73-216AA）
- Host Species：Rabbit
- Species Reactivity：Human
- Tested Applications：ELISA, WB, IHC, IF
- Clonality：Polyclonal
- Isotype：IgG
- Conjugate：Non-conjugated
- Buffer：Preservative： 0.03％ Proclin 300＜br /＞Constituents： 50％ Glycerol, 0.01M PBS, PH 7.4
- Form：Liquid
- Purification Method：＞95％, Protein G purified
- Target Names：KLRK1
- Research Area：Immunology
- サイズ：100ug
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-4352-16
KLRK1 Antibody 100ug
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86-4352-17
KLRK1 Antibody 50ug
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